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Points of Interest between Cape Girardeau, Missouri to Fayetteville, Arkansas

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picture of Cape Girardeau, Missouri

A Road Trip from Cape Girardeau, Missouri to Fayetteville, Arkansas

Embark on a scenic road trip from Cape Girardeau, Missouri, to Fayetteville, Arkansas, and explore many historic landmarks, museums, and parks that capture the essence of the American Midwest. This journey spans over 281 miles, crossing through rolling hills and charming small towns, and offers an array of experiences for the road trip enthusiasts.

Interesting Fact: Did you know that this stretch of the I-55 highway was once used by native tribes, French explorers, Spanish conquistadors, and American settlers as a trade route?

Located at around the halfway point, Salem, AR, is a hidden town in the Ozarks with a rich history of floods, fires, and tornadoes. Its courthouse square has been in use since the early 1900s and is a popular spot for festivals, parades, and live music performances.

This road trip takes approximately 4 hours if you follow the I-55 and the I-40 highways. However, the scenic route via the US-67 and the AR-412 may take up to 6 hours but promises to be more enchanting.

Top 5 Places to Visit

  1. Missouri State Park, Van Buren, MO Experience the beauty of the Missouri Ozarks at this state park, where hiking, fishing, and camping are the main attractions. If you love waterfalls, then you should visit the Big Spring, which is one of Missouri's largest springs and a natural wonder.

Point of Interest: Don't miss the opportunity to explore the Alley Mill, a historic site perched on the edge of a crystal-clear pond with a red-grist mill and a general store.

  1. Mark Twain Boyhood Home & Museum, Hannibal, MO Discover the childhood home of one of America's greatest writers, Mark Twain, and learn about his upbringing, his family, and his inspiration. The museum features interactive exhibits, historic buildings, and a comprehensive collection of Twain's works.

Point of Interest: Follow in Twain's footsteps and take a riverboat cruise on the Mississippi River, where he began his career as a steamboat pilot.

  1. Buffalo National River, Harrison, AR Explore one of the few remaining free-flowing rivers in the US and enjoy the scenic view of the Ozarks. The river offers a variety of recreational activities, such as kayaking, canoeing, fishing, and camping.

Point of Interest: Take a guided tour of the Mystic Caverns, a set of limestone caves that date back over 350 million years and contain stunning rock formations.

  1. Thorncrown Chapel, Eureka Springs, AR Experience the tranquility and serenity of this non-denominational chapel, which blends in perfectly with its surroundings and features a breathtaking design of glass and wood. The chapel is open to visitors all year round and is a popular spot for weddings and events.

Point of Interest: Visit the Christ of the Ozarks, a magnificent statue overlooking the town of Eureka Springs that was erected in 1966.

  1. Crystal Bridges Museum of American Art, Bentonville, AR Marvel at the impressive collection of American art from colonial times to the present day at this world-renowned museum. The museum's architecture itself is a piece of art, with winding trails, bridges, and ponds.

Point of Interest: Take a stroll in the museum's vast gardens, which feature sculptures, natural springs, and a Frank Lloyd Wright's house.

In conclusion, this road trip from Cape Girardeau, Missouri, to Fayetteville, Arkansas, offers a glimpse into the heartland of the US and showcases its rich cultural heritage and natural diversity. Whether you are a history buff, an art lover, or an outdoor enthusiast, this route has something to offer for everyone, and the experience is worth the drive.

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