A Road Trip from Cape Girardeau, MO to Fayetteville, AR

Are you looking for a fun road trip that takes you through the heart of the Midwest? Look no further than a drive from Cape Girardeau, Missouri to Fayetteville, Arkansas. With a variety of routes to choose from, there's something for everyone. Here's a breakdown of each option, including distance and estimated driving time.

Route 1: I-55 S and I-40 W

The most direct route is to take I-55 South to Memphis, Tennessee, then connect with I-40 West. This 362-mile trip should take approximately six hours. While there aren't many notable stops along the way, it's a great option if you're looking to get to your destination as quickly as possible.

Route 2: US-67 and US-167

For a more scenic route, consider taking US-67 South and then connecting with US-167 South. This route takes you through the Ozark Mountains and offers beautiful views along the way. The entire trip is 304 miles and should take about six hours. Be sure to stop in the charming town of Bald Knob, Arkansas, where you can visit the Arkansas Traveler Hometown Museum.

Route 3: US-62 and US-65

Another option is to take US-62 West and then connect with US-65 South. This route is slightly longer at 393 miles, but it's a great choice if you want to experience small towns and local flavor. Along the way, stop in the town of Harrison, Arkansas, where you can explore Mystic Caverns and take a guided tour of the underground caves.

Route 4: MO-142 W and AR-90 W

If you have extra time and want to explore more of Missouri and Arkansas, take MO-142 West and then turn onto AR-90 West. This route takes you through scenic farmland and charming small towns. The entire trip is approximately 427 miles and should take about eight hours. Don't miss the opportunity to stop in Mountain View, Arkansas, where you can take in a live music performance at the Ozark Folk Center State Park.

No matter which route you choose, be prepared for a beautiful drive through the heart of America. Take your time, enjoy the scenery, and be sure to make plenty of stops along the way. Whether you're looking for natural beauty or small town charm, this road trip has it all.