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Driving Time between Buffalo, New York and Nogales, Arizona

  • Halfway Point
  • Points of Interest
  • Travel Time
  • Travel Cost
A picture depicting driving

The Great American Road Trip: Buffalo, NY to Nogales, AZ

Ah, the open road. There's nothing quite like hitting the highways and byways of the good ol' USA. And what better destination than the sunny beaches of Nogales, Arizona? If you're starting your journey from Buffalo, New York, there are a few different routes you can take. Let's explore them together!

Option 1: The Most Direct Route

If you're in a hurry to get to Nogales and don't mind a long drive, the most direct route is I-90 West to I-80 West, then connect to I-25 South toward Albuquerque and finally switch to I-10 West that'll take you to Nogales.

Total distance: 2,516 miles

Total driving time: Approximately 38 hours

Recommendations: Break up the drive with stops at exciting destinations such as Chicago, St. Louis, and Santa Fe.

Option 2: The Southern Route

If you'd prefer to skip the Midwest and enjoy some Southern hospitality, this route might be for you. Take I-79 South to I-64 West to I-55 South in Missouri, then hit I-40 West toward Albuquerque and switch to I-10 West from there.

Total distance: around 2,767 miles

Total driving time: Approximately 41 hours

Recommendations: Stop at Nashville, Memphis, and the Grand Canyon!

Option 3: The Scenic Route

If you have the time and want to see some beautiful sights, take Route 66! Start on I-90 West to Chicago briefly, then connect to I-55 South (the classic Route 66), and use several other highways including I-40 West. Route 66 rejoins the 1-40 West, and you can take that all the way to Nogales.

Total distance: around 2,839 miles

Total driving time: Approximately 43 hours

Recommendations: Explore the landmarks of Route 66, including the Meramac Caverns, Blue Whale of Catoosa, Seligman, and the Petrified Forest National Park.

Option 4: The Coastal Route

If you're someone who loves the beach, then this is the route for you! Start on I-90 West, then take I-80 West to I-76 West to I-70 West to Denver, and use US highway 285 to Santa Fe. From there, take I-25 south to Albuquerque and switch to I-10 West to Nogales.

Total distance: around 3,133 miles

Total driving time: Approximately 46 hours

Recommendations: Make a pitstop in beautiful places like Cleveland, Asheville, Savannah, Santa Fe, Tucson, and Phoenix.

Conclusion

No matter which route you take, there's plenty to see and do on this epic road trip. As with all journeys, be sure to stay safe, hydrated, and entertained. Pack plenty of snacks, drinks, and entertainment for the long haul. And, most importantly, have an unforgettable time cruising across America.

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