Discover the top five must-visit destinations on a road trip from Buffalo, NY, to Houston, TX. Explore historic landmarks, breathtaking landscapes and unique cultures; the 1,400-mile journey is worth the 22-hour drive.

Planning a trip from Buffalo, NY to Houston, TX? Explore the different routes and costs based on current gas prices. Find the best route for your budget.

Explore the different routes and drive times from Buffalo, NY to Houston, TX! Whether you're looking for a quick trip or a scenic adventure, this post has you covered.