Embark on a Southern road trip from Durham to Savannah, with stops in charming Florence, lively Myrtle Beach, historic Beaufort, enchanting Savannah, and beautiful Charleston. Experience the best of Southern culture, history, and hospitality along the way. Pack your bags and hit the road for an unforgettable journey!

Planning a road trip from Durham, NC to Savannah, GA? Discover the costs involved based on current gas prices and different routes available. Choose the best option for your journey and hit the road!