Experience the best of a road trip from Durham, NC, to Pickens, SC, with stops at top attractions like the Nascar All-Star Museum and the Great Smoky Mountains National Park. Explore history, nature, and culture on this 150-mile journey through the Carolinas.

Discover the cost-effective route for your road trip from Durham, NC to Pickens, SC. Compare fuel costs, distances, and travel times to make the most of your journey.