Embark on a captivating road trip from Durham to Madison, exploring scenic stops like the Great Smoky Mountains, charming towns like Gatlinburg and Knoxville, and historic sites in Chattanooga and Huntsville. Discover the best of the Southeast along the way!

Planning a road trip from Durham, NC to Madison, AL? Discover the best route for your budget with insights on distance, time, and gas costs based on current prices. Get ready for a memorable journey while staying mindful of your expenses!