Embark on an unforgettable road trip from Durham to Las Vegas, exploring top destinations like the Great Smoky Mountains, Nashville, and Santa Fe. Discover cultural landmarks, natural wonders, and hidden gems on this 1,800-mile journey through America's heartland.

Planning a road trip from Durham, NC to Las Vegas, NV? Discover the costs of driving, including gas prices and tolls, for different routes. Choose wisely for a budget-friendly adventure!