Discover the top museums, parks, and landmarks on a road trip from Duncan, SC to Knoxville, TN. Explore the Blue Ridge Mountains and enjoy diverse attractions along the way. Uncover hidden gems and make unforgettable memories on this exciting journey.

Planning a trip from Duncan, South Carolina to Knoxville, Tennessee? Explore different routes, distances, times, and fuel costs to make the most of your journey. Find out which route suits your budget and preferences!