Embark on a scenic road trip from DuBois, PA, to Knoxville, TN, exploring national parks, historical sites, and urban gems along the way. Discover hidden gems and must-visit attractions on this unforgettable journey through the Appalachian region.

Planning a road trip from DuBois, PA, to Knoxville, TN? Discover the costs and routes with current gas prices. Compare distances, travel times, and total expenses for an informed journey.

Planning a road trip from DuBois, PA, to Knoxville, TN? Discover the fastest and most scenic routes, drive times based on traffic, and tips for an unforgettable journey in this helpful guide!