Discover the top attractions between Defiance, Ohio, and Syracuse, New York, including Presque Isle State Park, Chautauqua Institution, and more. Explore scenic stops and family-friendly destinations on this unforgettable road trip!

Discover the costs of driving from Defiance, Ohio to Syracuse, New York with detailed breakdowns of gas prices, tolls, and total expenses for two different routes. Plan your road trip budget effectively!

Planning a road trip from Defiance, Ohio, to Syracuse, New York? Discover the fastest and most scenic routes, estimated driving times, and tips for navigating traffic along the way. Prepare for a drive of 8-10 hours, with peak traffic impacting your journey. Safe travels!