Discover the top attractions on a road trip from Cowpens, SC to Johnson City, TN, including the Biltmore Estate and Great Smoky Mountains National Park. Plan your itinerary for an unforgettable journey through the Southeast!

Planning a road trip from Cowpens, SC to Johnson City, TN? Learn about the cost of driving, gas prices, and toll fees for different routes in this helpful guide.

Planning a road trip from Cowpens, SC to Johnson City, TN? Discover the fastest and slowest routes, driving times based on traffic patterns, and tips for a smooth journey in this detailed guide.