Discover the top five must-visit destinations on a road trip between Columbia, Tennessee, and Myrtle Beach, South Carolina. From charming towns to historic landmarks, embark on an unforgettable adventure through the heart of the South.

Planning a road trip from Columbia, TN to Myrtle Beach, SC? Discover the cost breakdown of different routes, gas prices, tolls, and travel times in this helpful guide.

Embark on a road trip from Columbia, TN to Myrtle Beach, SC! Discover different routes, distances, and driving times for a fun journey to the coast. Explore attractions along the way and make the most of your adventure!