Discover five unexpected places to stop on a road trip from Columbia to Orangeburg, South Carolina. From national parks to botanical gardens and cultural museums, uncover hidden gems along this scenic route. Indulge in local cuisine and immerse yourself in nature's splendor. A journey well worth taking.

Discover the most cost-effective route between Columbia and Orangeburg, SC based on current gas prices. Explore different options and find the best route for your trip.

Embark on a road trip from Columbia to Orangeburg, SC, and discover the best routes and scenic views along the way. Drive times and recommended stops included.