Discover five unexpected places to stop on a scenic drive from Columbia, SC to Lake City, SC. From unique gardens to charming towns, indulge in delicious local food and create lasting memories along the way.

Explore the cost of a trip from Columbia to Lake City, SC based on current gas prices. Compare routes, distances, and fuel costs to choose the most economical option for your journey.

Plan your road trip from Columbia to Lake City, SC with our guide! Discover the best routes, distances, and drive times for a fun and scenic journey through South Carolina.