Discover the top attractions on a road trip from Columbia, SC to Key West, FL. From historic plantations to space centers and vibrant streets, this adventure is packed with unforgettable experiences. Get ready to hit the road!

Planning a road trip from Columbia, SC to Key West, FL? Discover the cost breakdown of driving routes, distance, time, gas prices, and tolls to help you budget effectively.

Embark on a Southern road trip from Columbia, SC to Key West, FL with varying routes and travel times. Discover pit stops and attractions along the way for a memorable journey down the coast.