Embark on an exciting road trip from Columbia, South Carolina to Jacksonville, Florida, exploring fascinating museums, beautiful parks, and iconic landmarks along the way. Discover the top five must-visit destinations and make lasting memories on this diverse and captivating journey.

Plan your trip from Columbia, SC to Jacksonville, FL with our guide on the most cost-effective and efficient route, including estimated fuel costs and driving time.

Planning a road trip from Columbia, SC to Jacksonville, FL? Check out this guide for different routes, drive times, and recommended stops along the way!