Embark on an exciting road trip from Columbia, SC, to Baltimore, MD, and discover the highlights along the way. Explore Charleston's historic district, the Outer Banks' natural beauty, Annapolis' charm, Gettysburg's history, and the vibrant culture of Baltimore. An unforgettable journey awaits!

Planning a trip from Columbia, SC to Baltimore, MD? Explore route options, gas prices, and cost estimates to make the most economical choice for your journey.

Planning a road trip from Columbia, SC to Baltimore, MD? Learn about the fastest and slowest routes, distance, and driving times based on traffic patterns for a smooth journey.