Discover the top five attractions between Columbia, Missouri, and Ottumwa, Iowa, on a scenic road trip. From Mark Twain Cave to the iconic American Gothic House, explore fascinating landmarks and natural beauty along this unforgettable journey.

Planning a trip from Columbia, Missouri, to Ottumwa, Iowa? Explore cost-effective routes based on current gas prices. Discover the best route recommendations and estimated costs for a round trip.

Discover the best routes and pit stops for a road trip from Columbia, Missouri to Ottumwa, Iowa. From scenic drives to quick, direct routes, plan your journey with our helpful guide.