Discover the best things to do on a road trip from Columbia, Missouri to Gatlinburg, Tennessee. From iconic landmarks and national parks to bourbon tasting and country music history, this adventure offers unforgettable experiences and breathtaking scenery.

Discover the cost-effective route for a trip from Columbia, Missouri to Gatlinburg, Tennessee based on current gas prices. Explore different routes, costs, and driving times in this detailed guide.

Planning a road trip from Columbia, MO to Gatlinburg, TN? Find out the fastest and slowest routes, distances, and estimated drive times based on traffic patterns. Enjoy the scenic journey through the Midwest and Great Smoky Mountains!