Embark on a scenic road trip from Syracuse, NY, to Harrisburg, PA, and explore unexpected treasures along the way. Discover art, nature, and local cuisine at five distinctive stops that promise a memorable journey.

Planning a trip from Syracuse, New York to Harrisburg, Pennsylvania? Read this article to discover the most cost-effective route based on current gas prices and travel distance.

Planning a road trip from Syracuse, NY to Harrisburg, PA? Find out the fastest and slowest routes, distance, and estimated drive times for peak and low traffic. Enjoy a scenic drive or save time with the fastest route!