Discover the top five things to do on a road trip from Chicago, Illinois, to Gainesville, Florida, including a visit to the Biltmore Estate and rafting on the Ocoee River. Explore majestic mansions, tranquil mountains, and historic landmarks.

Planning a road trip from Chicago to Gainesville? Discover the cost of driving based on current gas prices, highlighting different routes, distance, time, and tolls. Get ready for an epic adventure!

Embark on an epic road trip from Chicago to Gainesville! Explore multiple routes, estimated drive times, and recommended pit stops along the way. Get ready for adventure, breathtaking scenery, and cherished memories on this unforgettable journey.