Discover the top five must-visit destinations on a road trip between Charleston, South Carolina and Orange City, Florida. From charming small towns to natural wonders, there's something for everyone on this East Coast adventure.

Planning a road trip from Charleston, SC to Orange City, FL? Read this article to estimate the cost of gas, explore route options, and find the best route.

Discover the best routes and drive times for a road trip from Charleston, SC to Orange City, FL. Explore coastal charm, historical sites, and natural beauty along the way. Buckle up for an unforgettable adventure through the Southern beauty!