Discover five unexpected places to stop during a road trip from Charleston, South Carolina to North Wilkesboro, North Carolina. From gardens to national parks, prepare to embark on an adventure through stunning natural beauty in the south.

Planning a road trip from Charleston, South Carolina to North Wilkesboro, North Carolina? Check out our breakdown of the cost of driving based on current gas prices and tolls for different routes.

Embark on a road trip from Charleston, SC to North Wilkesboro, NC and discover scenic routes, driving times, and must-visit stops along the way. Enjoy coastal charm, mountain escapes, and scenic shortcuts for an unforgettable adventure.