Discover unexpected stops on a road trip from Chapel Hill, NC, to Cincinnati, OH. Explore natural wonders, cuisine, and culture in our top picks along the route.

Find out the estimated cost of driving from Chapel Hill to Cincinnati based on current gas prices. Discover three different routes with distances, times, and costs highlighted in bold.

Discover the fastest and most scenic routes for driving from Chapel Hill, North Carolina to Cincinnati, Ohio. From I-75 N to Blue Ridge Parkway, find out how long it takes at peak and low traffic times. Embark on an unforgettable road trip!