Discover the best things to do on a road trip between Cayce, South Carolina, and Suffolk, Virginia. Explore national parks, living history museums, beautiful beaches, and entertainment complexes on this 400-mile journey.

Planning a trip from Cayce, South Carolina, to Suffolk, Virginia? Check out this article for the cost of transportation, including fuel costs and the best route to take.

Driving from Cayce, SC to Suffolk, VA can take between 7-8 hours. Read our guide to the fastest and slowest routes, and the impact of traffic patterns on travel time.