Take a road trip from Cayce, South Carolina to Fort Lauderdale, Florida and discover five unexpected places to stop along the way. Explore Mystic, Valdosta, Gainesville, St. Augustine, and West Palm Beach and try some of the local delicacies.

Planning a road trip from Cayce, SC to Fort Lauderdale, FL? Check out our guide with different routes, distance, time, gas, and toll costs to help with your budget.

Discover the best route from Cayce, South Carolina to Fort Lauderdale, Florida for your next road trip. Get driving times and recommendations for places to stop along the way.