Discover the best road trip adventure from Casey, Illinois, to Myrtle Beach, South Carolina. Explore the Abraham Lincoln Presidential Library, Mammoth Cave National Park, Great Smoky Mountains National Park, Seaworld Orlando, and Myrtle Beach.

Learn the cost of driving from Casey, Illinois to Myrtle Beach, South Carolina with different routes, gas prices, toll fees and the time it takes. Plan your road trip budget now!

Discover the best routes to drive from Casey, Illinois to Myrtle Beach, South Carolina. Plan your trip ahead with estimated driving times and tips for stops on the way.