"Discover the top 5 must-visit locations on a road trip from Cary, NC to Tuscaloosa, AL. From the Biltmore Estate to Downtown Nashville and the University of Alabama, explore the best of the South and its rich history."

Planning a trip from Cary, NC to Tuscaloosa, AL and curious about the cost of driving? Check out our guide with current gas and toll prices for different routes.

Planning a road trip from Cary, North Carolina to Tuscaloosa, Alabama? Check out our guide highlighting the different routes, distance, travel time, and recommended pit stops along the way.