Discover five unique places to stop on a road trip from Caruthersville, Missouri to Destin, Florida. Visit the iconic Gateway Arch, indulge in fudge, and enjoy breathtaking views on this 750-mile journey.

Discover the cost of driving from Caruthersville, Missouri to Destin, Florida. Explore three different routes, gas prices, and toll fees. Get an estimated cost of your road trip now!

Planning a road trip from Caruthersville to Destin? Explore different routes and travel times, with tips on must-see stops along the way. Choose your adventure and hit the road!