Discover the top five places to visit on a road trip from Carlisle, Pennsylvania to Gatlinburg, Tennessee. From natural wonders to theme parks, this journey has it all.

Planning a road trip from Carlisle, PA to Gatlinburg, TN? Check out this post for the cost of gas and tolls for three different routes based on current prices.

Discover three different routes for your road trip from Carlisle, Pennsylvania to Gatlinburg, Tennessee. Learn about driving distances, estimated times, and recommended stops.