Discover the top five places to visit on a trip from Carbondale, Illinois, to Clarksville, Tennessee, including a national park, historic landmarks, and charming towns.

Planning a road trip from Carbondale, Illinois to Clarksville, Tennessee? Check out our breakdown of the cost and time for three possible routes, including tolls and gas prices.

Discover the fastest and slowest routes for driving from Carbondale, Illinois to Clarksville, Tennessee. Plan your trip with insights on driving time, traffic patterns, and route options.