Embark on a road trip from Cape Girardeau, MO to Nags Head, NC and discover the top attractions along the way, including the Great Smoky Mountains, Blue Ridge Parkway, Outer Banks, Wright Brothers Memorial, and Jockey's Ridge State Park. A travel adventure like no other!

Discover the cost of a road trip from Cape Girardeau, Missouri to Nags Head, North Carolina based on current gas prices. Explore different route options and find the best recommendation for an economical journey.

Embark on an epic road trip from Cape Girardeau, Missouri to Nags Head, North Carolina with our guide! Discover different routes, distances, and driving times, and get recommendations for amazing stops along the way. Are you ready for the ultimate adventure?