Discover five must-see stops in between Cape Coral, Florida, and New Orleans, Louisiana. Explore the history in St. Augustine and Baton Rouge, indulge in Southern charm in Mobile, and relax on Biloxi's beaches.

Plan your trip between Cape Coral, Florida, and New Orleans, Louisiana, with this guide to the three main routes options. Compare costs and distances to choose the best option for you.

Discover the best routes to travel between Cape Coral, Florida, and New Orleans, Louisiana. Explore scenic drives and historic landmarks along the way. Plan your next epic road trip adventure today!