Discover the top 5 things to do on a road trip from Cape Coral to Naples, Florida, including Sanibel Island and The Edison & Ford Winter Estates. Enjoy the natural beauty of the gulf, explore historic landmarks, and see amazing wildlife.

Planning a road trip from Cape Coral, Florida to Naples, Florida? Read this guide to know the cost of each route based on current gas prices and tolls.

Discover the different routes and travel times for a road trip from Cape Coral to Naples, Florida. Explore scenic paths and find places to stop along the way.