Discover the top five popular attractions to see on a road trip from Buffalo, New York to Saint Petersburg, Florida. From Niagara Falls to the Smoky Mountains and the Salvador Dali Museum, explore these must-visit destinations.

Planning a road trip from Buffalo to Saint Petersburg, Florida? Read this post to find out the cost of different routes based on current gas prices and tolls.

Planning a road trip from Buffalo to Saint Petersburg? Learn about the fastest and most scenic routes, along with estimated travel times based on traffic patterns.