Embark on a road trip from Buffalo to St. Louis and discover museums, parks, and landmarks. Niagara Falls, Rock and Roll Hall of Fame Museum and City Museum are must-visits!

Planning a road trip from Buffalo, NY to St. Louis, MO? Here's a breakdown of gas prices and toll expenses for 4 popular routes, including distance and time.

Planning a road trip from Buffalo to Saint Louis? Check out our routes, recommendations, and drive times for a fun and memorable journey.