Discover the five best places to visit on a road trip from Buffalo, NY to Orlando, FL. From horses and bourbon in Lexington to the Kennedy Space Center in Florida, this trip is full of adventure and history.

Discover the best and most cost-effective routes for traveling between Buffalo, New York and Orlando, Florida. Learn about the costs and distances for driving, flying, taking the train, or bus.

Planning a road trip from Buffalo, New York to Orlando, Florida? We've got you covered with the best routes and estimated driving times to help you prepare for your adventure.