Discover the top 5 must-visit attractions to add to your road trip itinerary from Buffalo, NY to Myrtle Beach, SC. Highlights include Hershey's Chocolate World, the Appalachian Mountains, and Myrtle Beach.

Planning a road trip from Buffalo, NY, to Myrtle Beach, SC? Read this article for a comparison of routes based on gas prices to help you save money and time.

Plan your road trip from Buffalo, NY to Myrtle Beach, SC - Explore the fastest and slowest routes, distances, and peak and low traffic driving times.