Take a remarkable road trip from Buffalo, New York, to Los Gatos, California, and explore some of America's greatest natural landmarks and iconic monuments. Enjoy Yellowstone National Park, Mount Rushmore National Memorial, the Grand Canyon, Las Vegas, and San Francisco along the way.

Learn the estimated cost of driving from Buffalo, NY to Los Gatos, CA using different routes based on current gas prices and toll fees. Plan your road trip budget accordingly!

Embark on an unforgettable journey from Buffalo, New York to Los Gatos, California with our guide. Discover the best routes, driving times, and recommended stops in between.