Discover the top five must-visit places on a road trip between Buffalo, New York, and Jacksonville, Florida. From stunning architecture at Fallingwater to the haunted history of Savannah, this road trip has it all.

Planning a road trip from Buffalo to Jacksonville? Get insights on the distances, costs, and recommendations for the best route to take for a safe and enjoyable journey.

Planning a road trip from Buffalo, NY to Jacksonville, FL? Learn the fastest and slowest routes, distance, and driving times based on traffic patterns in this helpful guide.