Discover the top five must-see attractions on a road trip from Buffalo, NY to Festus, MO. Explore Niagara Falls, the Rock and Roll Hall of Fame, Mammoth Cave National Park, the Gateway Arch, and Silver Dollar City.

Planning a road trip from Buffalo, NY to Festus, MO? Check out our guide for the cost of driving, including gas prices and tolls for three different routes.

Planning a road trip from Buffalo, NY to Festus, MO? Get insights into the fastest and slowest routes, distance, and peak and low traffic times to reach your destination. Check out our guide now!