Embark on an unforgettable road trip from Buffalo, New York to Effingham, Illinois. Discover the top five attractions along the way, including Niagara Falls, the Rock & Roll Hall of Fame, and the iconic Gateway Arch. Get ready for a journey filled with majestic wonders and historic treasures!

Planning a trip from Buffalo to Effingham? Discover the cost of different routes based on current gas prices and choose the best one for your journey. Find the most cost-effective route in this informative guide.

Embark on an exciting road trip from Buffalo, NY, to Effingham, IL! Discover the fastest and scenic routes, estimated drive times, and tips to beat traffic. Plan your adventure wisely and make the most of your journey!