Discover the top museums, parks, and landmarks to visit on a road trip from Buffalo to City of Poughkeepsie in this guide. Explore natural wonders, historical sites, and more along the way.

Planning a trip between Buffalo and Poughkeepsie, but unsure about the cost? Read our guide on different routes, distance, and cost breakdowns based on 2021 gas prices. Choose the best route and save money.

Explore the different routes, distances, and driving times from Buffalo to Poughkeepsie. Discover the best places to stop along the way, including museums, parks, and vineyards.