Discover five unexpected places to stop on a road trip from Buffalo, New York to Brandon, Florida. From aviation history to surreal art, experience unique attractions and favorite foods along the way.

Discover the best route for your trip between Buffalo, New York and Brandon, Florida based on current gas prices. Compare the cost and distance of each route and plan your trip now.

Find out how long it takes to drive from Buffalo, NY to Brandon, FL with this comprehensive guide. Discover the fastest and most scenic routes, driving times, and traffic conditions.