Discover five unique destinations to visit on a Missouri road trip from Buffalo to Nixa. From state parks to underground mines, there's something for everyone.

Plan a road trip from Buffalo, MO, to Nixa, MO, by checking out the different routes, times, and costs available based on current gas prices.

Discover the best routes and travel times for your road trip from Buffalo, MO to Nixa, MO. From fast-paced highways to scenic routes, we've got you covered. Plus, our recommendations for must-visit places along the way.