Discover the top five things to do on a road trip from Brownfield, Maine, to Bluffton, South Carolina, covering 1,200 miles and taking about 20 hours. Explore the Smithsonian's National Air and Space Museum, tour the magnificent Biltmore Estate, and relax at the charming coastal town of Beaufort, among others.

Planning a road trip from Brownfield, Maine, to Bluffton, South Carolina? This article breaks down the cost of different routes and recommends the most cost-effective option.

Discover the fastest and slowest routes, the distances, and drive times based on traffic patterns when driving from Brownfield, Maine to Bluffton, South Carolina. Find out which roads are best for scenic routes and which ones to avoid during peak traffic times.