This article highlights the top five must-visit destinations on a road trip route between Bloomington, Illinois, and Biloxi, Mississippi. Explore historic sites like the St. Louis Gateway Arch, Elvis Presley's Graceland mansion, and the National Civil Rights Museum, and end your journey with the iconic Biloxi Lighthouse.

Discover the most affordable route for a road trip from Bloomington, Illinois, to Biloxi, Mississippi, based on current gas prices. Compare the costs and distances of each possible route to make the most informed decision.

Planning a road trip from Bloomington, IL to Biloxi, MS? Read on for fast and scenic routes and driving times based on peak traffic and local events to avoid any unwanted surprises.