Discover the top five best places to visit on a road trip between Birmingham, Alabama and Florence, South Carolina. From beaches to national monuments, this itinerary has it all!

Planning a trip from Birmingham, Alabama to Florence, South Carolina? Read this guide to determine the cost of gas, flight tickets, and rental cars for each route. Find the best option for your budget!

Planning a road trip from Birmingham, Alabama to Florence, South Carolina? Check out this post for the different routes available, drive times, and traffic patterns.