Discover the top places to visit when driving from Barstow to San Luis Obispo, California, including Calico Ghost Town, Mojave National Preserve, and Santa Barbara. Hit the open road and take in the stunning landscapes and unique landmarks along the way.

Plan your road trip from Barstow to San Luis Obispo with our breakdown of the different routes, distance, time, and cost, including gas and toll prices.

Planning a road trip from Barstow to San Luis Obispo? Read this blog post to learn about the fastest and slowest routes, distance, and driving time based on traffic patterns.